HAVOC, A BIOINFORMATIC PIPELINE FOR REFERENCE-BASED CONSENSUS ASSEMBLY AND LINEAGE ASSIGNMENT FOR SARS-COV-2 SEQUENCES

HAVoC, a bioinformatic pipeline for reference-based consensus assembly and lineage assignment for SARS-CoV-2 sequences

Abstract Background SARS-CoV-2 related research has increased in importance worldwide since December 2019.Several new variants of SARS-CoV-2 have emerged globally, of which the most notable and concerning currently are the UK variant B.1.1.7, the South African variant B1.351 and the Brazilian variant P.1.Detecting and monitoring novel variants is e

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Nationwide safety surveillance of COVID-19 mRNA vaccines following primary series and first booster vaccination in Singapore

Background: The real-world safety profile of COVID-19 mRNA vaccines remains incompletely elucidated.Methods: We performed a nationwide post-market safety surveillance analysis in Singapore, on vacinees aged 5 years and older, through mid-September 2022.Observed-over-expected (O/E) analyses were performed to identify potential safety signals among e

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